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Terminal Complement Complex

《英文msh詞典》Terminal Complement Complex
[入口詞] Terminal Complement Complex
[主題詞] Complement Membrane Attack Complex
[英文釋義] The assembly of complement plasma glycoproteins C5b,C6,C7,C8,and polymeric C9 as a group on biological membranes. The complex forms transmembrane channels which displace lipid molecules and other constituents,thus disrupting the phospholipid bilayer of target cells leading to cell lysis by osmotic leakage. The formation of the membrane attack complex is the terminal step in the complement cascade.

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